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onix v1 microfluidics platform  (CellASIC Corporation)

 
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    CellASIC Corporation onix v1 microfluidics platform
    Onix V1 Microfluidics Platform, supplied by CellASIC Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/onix v1 microfluidics platform/product/CellASIC Corporation
    Average 90 stars, based on 1 article reviews
    onix v1 microfluidics platform - by Bioz Stars, 2026-02
    90/100 stars

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    An experiment schematic is included in the panel. BCG darG-sgRNA and BCG carrying an empty vector were pretreated for 48 h with 200 ng/ml ATC, then loaded into a microfluidic device. The bacteria were imaged every hour for 59 h, with continued ATC treatment. BCG-vector control bacilli divide over 59 h ( A – C ), whereas BCG darG-sgRNA stop dividing and elongate ( D – F ). An example is circled in each treatment. .

    Journal: The EMBO Journal

    Article Title: Control of replication and gene expression by ADP-ribosylation of DNA in Mycobacterium tuberculosis

    doi: 10.1038/s44318-025-00451-y

    Figure Lengend Snippet: An experiment schematic is included in the panel. BCG darG-sgRNA and BCG carrying an empty vector were pretreated for 48 h with 200 ng/ml ATC, then loaded into a microfluidic device. The bacteria were imaged every hour for 59 h, with continued ATC treatment. BCG-vector control bacilli divide over 59 h ( A – C ), whereas BCG darG-sgRNA stop dividing and elongate ( D – F ). An example is circled in each treatment. .

    Article Snippet: For microscopy experiments, minimally darG -silenced bacilli were harvested after 7 days of treatment and loaded into a CellAsic ONIX Microfluidic Platform using a plate for bacterial cells.

    Techniques: Plasmid Preparation, Bacteria, Control

    An experiment schematic is included in the panel. BCG darG-sgRNA were minimally inhibited with ATC in a microtitre plate for 7 days, and loaded into a microfluidic device ( A ). After 12 h, ATC was washed out of the device ( B ). The bacterium marked with a white arrow was followed over time ( C ). After 16 h in fresh medium, division occurs at one pole ( D – F ). After 58 in fresh medium, branching occurs at the other pole ( G ) but is followed by swelling ( H ) and necrosis ( I ).

    Journal: The EMBO Journal

    Article Title: Control of replication and gene expression by ADP-ribosylation of DNA in Mycobacterium tuberculosis

    doi: 10.1038/s44318-025-00451-y

    Figure Lengend Snippet: An experiment schematic is included in the panel. BCG darG-sgRNA were minimally inhibited with ATC in a microtitre plate for 7 days, and loaded into a microfluidic device ( A ). After 12 h, ATC was washed out of the device ( B ). The bacterium marked with a white arrow was followed over time ( C ). After 16 h in fresh medium, division occurs at one pole ( D – F ). After 58 in fresh medium, branching occurs at the other pole ( G ) but is followed by swelling ( H ) and necrosis ( I ).

    Article Snippet: For microscopy experiments, minimally darG -silenced bacilli were harvested after 7 days of treatment and loaded into a CellAsic ONIX Microfluidic Platform using a plate for bacterial cells.

    Techniques: